Real-time control of lesion size based on reflectance images

Maya R. Jerath, Danielle Kaisig, Henry G. Rylander, Ashley J. Welch

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations


Laser-induced lesion size is controlled in real time based on a two dimensional reflectance image recorded by a CCD array during lesion formation. A feedback system using components of the reflectance image achieves uniform lesions by compensating for light absorption variability in biological media. Lesions are formed in a phantom using an argon laser to simulate retinal photocoagulation. The tissue model consists of an absorptive high temperature black paint layer and an egg white protein layer. Reflectance images are acquired as the lesion forms at a standard frame rate using a 512 × 512 CCD camera attached to an ITI 151 series image processor and a Sun 3/260 computer. A shutter controlled by the computer is closed when certain preset conditions are met in the images. Results show a low variance in the sizes of the lesions (diameter or depth) produced under different irradiation conditions and the ability to produce lesions of a predefined size under varying illumination conditions. Real time control from reflectance images based on certain parameters is demonstrated as a feasible method of controlling lesion size.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Int Soc for Optical Engineering
Number of pages11
ISBN (Print)0819407909
StatePublished - Dec 1 1992
EventOphthalmic Technologies II - Los Angeles, CA, USA
Duration: Jan 19 1992Jan 21 1992

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


ConferenceOphthalmic Technologies II
CityLos Angeles, CA, USA


Dive into the research topics of 'Real-time control of lesion size based on reflectance images'. Together they form a unique fingerprint.

Cite this