Reactive fibrohistiocytic proliferation simulating fibrous histiocytoma

D. C. Snover, G. Phillips, L. P. Dehner

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


A pelvic nodule was excised at the time of reexploration of the abdomen in a 32-year-old woman who had previously had a malignant germ cell tumor with a mixed histologic pattern of the right ovary. The 3-cm firm lesion from the right vaginal apex was composed predominantly of spindle cells with a prominent storiform pattern. Some findings, such as the presence of foamy histiocytes and a focal foreign body reaction with polarizable material, were atypical for a lesion otherwise quite acceptable histologically as a fibrous histiocytoma. Ultrastructural findings also tended to support the reactive rather than neoplastic nature of this mass. There is a similarity to the silica reaction described by Weiss and co-workers.

Original languageEnglish
Pages (from-to)232-235
Number of pages4
JournalAmerican journal of clinical pathology
Issue number2
StatePublished - Jan 1 1981


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