Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer's Disease Pathology

Jason D. Ulrich; Tien Phat Huynh; David M. Holtzman

doi:10.1016/j.neuron.2015.10.008

Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer's Disease Pathology

Jason D. Ulrich, Tien Phat Huynh, David M. Holtzman

Research output: Contribution to journal › Short survey › peer-review

16 Scopus citations

Abstract

Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction. Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction.

Original language	English
Pages (from-to)	237-239
Number of pages	3
Journal	Neuron
Volume	88
Issue number	2
DOIs	https://doi.org/10.1016/j.neuron.2015.10.008
State	Published - Oct 21 2015

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10.1016/j.neuron.2015.10.008

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abstract = "Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction. Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction.",

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AU - Huynh, Tien Phat

AU - Holtzman, David M.

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AB - Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction. Blood-brain barrier disruption is believed to occur in Alzheimer's disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction.

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Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer's Disease Pathology

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