An albumin-like protein (pro-albumin) has been isolated from rat liver microsomal albumin by isoelectric focusing. Unlike intracellular serum albumin, it becomes highly radioactive in the course of albumin biosynthesis at the expense of labeled amino acids in vivo. The albumin-like protein is immunologically indistinguishable from rat serum albumin and has the same (or similar) N-terminus: glutamate (or glutamine). Maps of tryptic peptides suggest that the albumin-like protein may be a peptide derivative of serum albumin.
|Number of pages||7|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Nov 1 1973|