Abstract
Intermediate lobes isolated from rat pituitary glands incorporated [ 35S]sulfate into pro-opiomelanocortin and other adrenocorticotropic hormone-containing peptides. Incubation of intermediate lobes in medium containing the arginine analog canavanine inhibited the cleavage of pro-opiomelanocortin into smaller products. Pro-opiomelanocortin that accumulated in the presence of canavanine was also sulfated.
Original language | English |
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Pages (from-to) | 63-64 |
Number of pages | 2 |
Journal | Science |
Volume | 217 |
Issue number | 4554 |
DOIs | |
State | Published - 1982 |