Rare Variant of Intravascular Large B-Cell Lymphoma with Hemophagocytic Syndrome

Joseph S. Donald; Nick Barnthouse; Delphine L. Chen

doi:10.1097/RLU.0000000000001969

Rare Variant of Intravascular Large B-Cell Lymphoma with Hemophagocytic Syndrome

Joseph S. Donald, Nick Barnthouse, Delphine L. Chen

Division of Radiological Sciences

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Intravascular lymphoma (IVL) is a rare subtype of diffuse large B-cell lymphoma characterized by a clonal proliferation of lymphocytes restricted to the intravascular space. We present the case of a 60-year-old man with hemophagocytic syndrome secondary to IVL. ¹⁸F-FDG PET/CT demonstrated hepatosplenomegaly with marked diffuse hepatic, splenic, and bone marrow hypermetabolism. The case report illustrates the imaging findings of this uncommon variant of IVL.

Original language	English
Pages (from-to)	e125-e126
Journal	Clinical nuclear medicine
Volume	43
Issue number	4
DOIs	https://doi.org/10.1097/RLU.0000000000001969
State	Published - Apr 1 2018

Keywords

hemophagocytic syndrome
hepatosplenomegaly
intravascular lymphoma

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10.1097/RLU.0000000000001969

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abstract = "Intravascular lymphoma (IVL) is a rare subtype of diffuse large B-cell lymphoma characterized by a clonal proliferation of lymphocytes restricted to the intravascular space. We present the case of a 60-year-old man with hemophagocytic syndrome secondary to IVL. 18F-FDG PET/CT demonstrated hepatosplenomegaly with marked diffuse hepatic, splenic, and bone marrow hypermetabolism. The case report illustrates the imaging findings of this uncommon variant of IVL.",

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AU - Barnthouse, Nick

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N2 - Intravascular lymphoma (IVL) is a rare subtype of diffuse large B-cell lymphoma characterized by a clonal proliferation of lymphocytes restricted to the intravascular space. We present the case of a 60-year-old man with hemophagocytic syndrome secondary to IVL. 18F-FDG PET/CT demonstrated hepatosplenomegaly with marked diffuse hepatic, splenic, and bone marrow hypermetabolism. The case report illustrates the imaging findings of this uncommon variant of IVL.

AB - Intravascular lymphoma (IVL) is a rare subtype of diffuse large B-cell lymphoma characterized by a clonal proliferation of lymphocytes restricted to the intravascular space. We present the case of a 60-year-old man with hemophagocytic syndrome secondary to IVL. 18F-FDG PET/CT demonstrated hepatosplenomegaly with marked diffuse hepatic, splenic, and bone marrow hypermetabolism. The case report illustrates the imaging findings of this uncommon variant of IVL.

KW - hemophagocytic syndrome

KW - hepatosplenomegaly

KW - intravascular lymphoma

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ER -

Rare Variant of Intravascular Large B-Cell Lymphoma with Hemophagocytic Syndrome

Abstract

Keywords

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