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Rapid manufacturing of non-activated potent CAR T cells
Saba Ghassemi
, Joseph S. Durgin
, Selene Nunez-Cruz
, Jai Patel
, John Leferovich
,
Marilia Pinzone
, Feng Shen
, Katherine D. Cummins
, Gabriela Plesa
, Vito Adrian Cantu
, Shantan Reddy
, Frederic D. Bushman
, Saar I. Gill
, Una O’Doherty
, Roddy S. O’Connor
, Michael C. Milone
Division of Infectious Diseases
Research output
:
Contribution to journal
›
Article
›
peer-review
213
Scopus citations
Overview
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Keyphrases
Chimeric Antigen Receptor T Cells (CAR-T)
100%
Non-interactive
100%
Rapid Manufacturing
100%
T Cells
28%
Viral Transduction
28%
T Cell Activation
14%
Hematological Malignancies
14%
Clinical Response
14%
B Cells
14%
Peripheral Blood
14%
Cell-derived
14%
Culture Vessel
14%
Ex Vivo Expansion
14%
Mouse Xenograft Model
14%
In Vivo Activity
14%
Surface-to-volume Ratio
14%
Human Leukemia
14%
Production Cost Reduction
14%
Engineering
T Cell Receptor
100%
Rapid Manufacturing
100%
T Cell
42%
Applicability
14%
B Cell
14%
Peripheral Blood
14%
Clinical Response
14%
Durables
14%
Surface-Area-to-Volume Ratio
14%
Medicine and Dentistry
Chimeric Antigen Receptor T-Cell
100%
Ex Vivo
28%
T Cell
28%
Viral Gene Delivery System
28%
Antileukemic Agent
28%
Health Care Cost
14%
T Cell Activation
14%
B Cell
14%
Hematologic Malignancy
14%
Xenograft
14%
Leukemia
14%
Immunology and Microbiology
Chimeric Antigen Receptor T-Cell
100%
T Cell
28%
Viral Gene Delivery System
28%
T Cell Activation
14%
B Cell
14%
Xenograft
14%
Surface Area
14%