Keyphrases
Metabolic Flexibility
100%
Dietary Fat
100%
Initiating Event
100%
Diet-induced
100%
Pyruvate Dehydrogenase
100%
Induced Loss
100%
Pyruvate Dehydrogenase Kinase 4 (PDK4)
100%
Fatty Acids
75%
High-fat Diet
75%
Insulin Signaling
50%
Energy Production
50%
Glucose Oxidation
50%
Cardiac Mitochondria
50%
Knock-in Mouse Model
25%
Cardiovascular Disease
25%
Pyruvate Dehydrogenase Activity
25%
Rapid Decline
25%
Response Change
25%
Mitochondria
25%
Metabolic Changes
25%
Glucose Transporter 4 (GLUT4)
25%
Diabetic
25%
Glycolytic Enzymes
25%
Akt Phosphorylation
25%
First Day
25%
Cardiac Function
25%
Fatty Acid Oxidation
25%
Glucose Level
25%
Four-level
25%
Metabolic Response
25%
Dietary Intervention
25%
Low-fat Diet
25%
Substrate Availability
25%
Overnight Fast
25%
Metabolic Inflexibility
25%
Energetic Stress
25%
Mitochondrium
25%
Medicine and Dentistry
Fat Intake
100%
Pyruvate Dehydrogenase
100%
Pyruvate Dehydrogenase Kinase 4
80%
Mitochondrion
60%
Fatty Acid
60%
Insulin Signaling
40%
Pyruvic Acid
40%
High Fat Food
40%
Cardiovascular Disease
20%
Glycolytic Enzyme
20%
Fatty Acid Oxidation
20%
Heart Function
20%
Diet Therapy
20%
Glucose Transporter 4
20%
Energy Transfer
20%
Glucose Oxidation
20%
Low Fat Diet
20%
Protein Kinase B
20%
Knockout Mouse
20%
Biochemistry, Genetics and Molecular Biology
Pyruvate Dehydrogenase
100%
Dietary Fat
100%
Pyruvate Dehydrogenase Kinase
80%
Mitochondrion
60%
Insulin Signaling
40%
Energy Yield
40%
Enzyme
20%
Knockout Mouse
20%
Metabolic Pathway
20%
Energy Transfer
20%
Beta Oxidation
20%
Heart Function
20%
Glucose Oxidation
20%
Glucose Transporter
20%
Protein Kinase B
20%
Agricultural and Biological Sciences
Dietary Fat
100%
Oxidoreductase
100%
Fatty Acids
44%
Mouse
33%
Mitochondrion
33%
High Fat Food
22%
Cardiovascular System
11%
Glucose Transporter
11%
Low Fat Diet
11%