Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry

Mark D. Gonzalez; Carol J. Weber; Carey Ann D. Burnham

doi:10.1016/j.diagmicrobio.2016.02.018

Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry

Mark D. Gonzalez
, Carol J. Weber
, Carey Ann D. Burnham

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We performed a retrospective analysis of a simple modification to MALDI-TOF MS for microorganism identification to accurately improve the turnaround time (TAT) for identification of Enterobacteriaceae recovered in blood cultures. Relative to standard MALDI-TOF MS procedures, we reduced TAT from 28.3 (n = 90) to 21.2 h (n = 107).

Original language	English
Pages (from-to)	133-135
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	85
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2016.02.018
State	Published - Jun 1 2016

Keywords

Anaerobes
Blood cultures
Enterobacteriaceae
MALDI-TOF MS
Non-fermenters
Yeast

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10.1016/j.diagmicrobio.2016.02.018

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title = "Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry",

abstract = "We performed a retrospective analysis of a simple modification to MALDI-TOF MS for microorganism identification to accurately improve the turnaround time (TAT) for identification of Enterobacteriaceae recovered in blood cultures. Relative to standard MALDI-TOF MS procedures, we reduced TAT from 28.3 (n = 90) to 21.2 h (n = 107).",

keywords = "Anaerobes, Blood cultures, Enterobacteriaceae, MALDI-TOF MS, Non-fermenters, Yeast",

author = "Gonzalez, \{Mark D.\} and Weber, \{Carol J.\} and Burnham, \{Carey Ann D.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

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day = "1",

doi = "10.1016/j.diagmicrobio.2016.02.018",

language = "English",

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Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry. / Gonzalez, Mark D.; Weber, Carol J.; Burnham, Carey Ann D.
In: Diagnostic Microbiology and Infectious Disease, Vol. 85, No. 2, 01.06.2016, p. 133-135.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry

AU - Gonzalez, Mark D.

AU - Weber, Carol J.

AU - Burnham, Carey Ann D.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - We performed a retrospective analysis of a simple modification to MALDI-TOF MS for microorganism identification to accurately improve the turnaround time (TAT) for identification of Enterobacteriaceae recovered in blood cultures. Relative to standard MALDI-TOF MS procedures, we reduced TAT from 28.3 (n = 90) to 21.2 h (n = 107).

AB - We performed a retrospective analysis of a simple modification to MALDI-TOF MS for microorganism identification to accurately improve the turnaround time (TAT) for identification of Enterobacteriaceae recovered in blood cultures. Relative to standard MALDI-TOF MS procedures, we reduced TAT from 28.3 (n = 90) to 21.2 h (n = 107).

KW - Anaerobes

KW - Blood cultures

KW - Enterobacteriaceae

KW - MALDI-TOF MS

KW - Non-fermenters

KW - Yeast

UR - https://www.scopus.com/pages/publications/84964343760

U2 - 10.1016/j.diagmicrobio.2016.02.018

DO - 10.1016/j.diagmicrobio.2016.02.018

M3 - Article

C2 - 27117518

AN - SCOPUS:84964343760

SN - 0732-8893

VL - 85

SP - 133

EP - 135

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 2

ER -

Rapid identification of microorganisms from positive blood cultures by testing early growth on solid media using matrix-assisted laser desorption ionization-time of flight mass spectrometry

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Keywords

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