TY - JOUR
T1 - Rapid Fire
T2 - Infectious Disease Emergencies in Patients with Cancer
AU - Charshafian, Stephanie
AU - Liang, Stephen Y.
N1 - Funding Information:
Disclosure: S. Charshafian reports no conflicts of interest and no financial disclosures. S.Y. Liang reports no conflicts of interest in this work. S.Y. Liang is the recipient of a KM1 Comparative Effectiveness Research Career Development Award ( KM1CA156708-01 ) and received support through the Clinical and Translational Science Award (CTSA) program ( UL1RR024992 ) of the National Center for Advancing Translational Sciences as well as the Barnes-Jewish Patient Safety & Quality Career Development Program, which is funded by the Foundation for Barnes-Jewish Hospital .
Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/8
Y1 - 2018/8
N2 - Patients with cancer can be immunocompromised because of their underlying malignancy as well as the medical therapies with which they are treated. Infections frequently present atypically and can be challenging to diagnose. The spectrum of infectious diseases encountered in patients receiving chemotherapy, hematopoietic stem cell transplant, and immunotherapy is broad depending on the depth of immunosuppression. Early recognition of infectious processes followed by appropriate diagnostic testing, imaging, and empiric antibiotic therapy in the emergency department are critical to providing optimal care and improving survival in this complex patient population.
AB - Patients with cancer can be immunocompromised because of their underlying malignancy as well as the medical therapies with which they are treated. Infections frequently present atypically and can be challenging to diagnose. The spectrum of infectious diseases encountered in patients receiving chemotherapy, hematopoietic stem cell transplant, and immunotherapy is broad depending on the depth of immunosuppression. Early recognition of infectious processes followed by appropriate diagnostic testing, imaging, and empiric antibiotic therapy in the emergency department are critical to providing optimal care and improving survival in this complex patient population.
KW - Cancer
KW - Cytokine release syndrome
KW - Emergency department
KW - Hematopoietic stem cell transplant
KW - Infections
KW - Neutropenic fever
UR - http://www.scopus.com/inward/record.url?scp=85048515026&partnerID=8YFLogxK
U2 - 10.1016/j.emc.2018.04.001
DO - 10.1016/j.emc.2018.04.001
M3 - Review article
C2 - 30037437
AN - SCOPUS:85048515026
SN - 0733-8627
VL - 36
SP - 493
EP - 516
JO - Emergency Medicine Clinics of North America
JF - Emergency Medicine Clinics of North America
IS - 3
ER -