Rapid eye movement sleep behavior disorder in adults younger than 50 years of age

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22 Scopus citations

Abstract

Rapid eye movement (REM) sleep behavior disorder (RBD) occurring prior to age 50 is termed early-onset RBD. Early-onset RBD comprises a substantial minority of cases, and demonstrates the differences in demographics, comorbidities, and clinical considerations from previously described typical RBD with onset >50. years. The world literature on RBD is reviewed with specific focus on features that distinguish early-onset RBD, including more gender parity, increased proportion of idiopathic cases, increased proportion of cases associated with narcolepsy, parasomnia overlap disorder, antidepressants, and possibly autoimmune disorders, and clinical presentation.

Original languageEnglish
Pages (from-to)768-774
Number of pages7
JournalSleep Medicine
Volume14
Issue number8
DOIs
StatePublished - Aug 2013
Externally publishedYes

Keywords

  • Antidepressant
  • Autoimmune
  • Narcolepsy
  • Parasomnia
  • Parasomnia overlap disorder (POD)
  • REM sleep behavior disorder (RBD)

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