Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo

Christine M. O'Brien; Elizabeth Vargis; Bibhash C. Paria; Kelly A. Bennett; Anita Mahadevan-Jansen; Jeff Reese

doi:10.1111/apa.12630

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo

Christine M. O'Brien, Elizabeth Vargis, Bibhash C. Paria, Kelly A. Bennett, Anita Mahadevan-Jansen, Jeff Reese

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods. Conclusion Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.

Original language	English
Pages (from-to)	715-721
Number of pages	7
Journal	Acta Paediatrica, International Journal of Paediatrics
Volume	103
Issue number	7
DOIs	https://doi.org/10.1111/apa.12630
State	Published - Jul 2014

Keywords

Cervical remodelling
Cervix
Parturition
Pregnancy
Preterm birth

Access to Document

10.1111/apa.12630

Cite this

@article{d1875dabd0ba4334b6738a96171c8284,

title = "Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo",

abstract = "The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods. Conclusion Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.",

keywords = "Cervical remodelling, Cervix, Parturition, Pregnancy, Preterm birth",

author = "O'Brien, {Christine M.} and Elizabeth Vargis and Paria, {Bibhash C.} and Bennett, {Kelly A.} and Anita Mahadevan-Jansen and Jeff Reese",

year = "2014",

month = jul,

doi = "10.1111/apa.12630",

language = "English",

volume = "103",

pages = "715--721",

journal = "Acta Paediatrica, International Journal of Paediatrics",

issn = "0803-5253",

number = "7",

}

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo. / O'Brien, Christine M.; Vargis, Elizabeth; Paria, Bibhash C.; Bennett, Kelly A.; Mahadevan-Jansen, Anita; Reese, Jeff.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 103, No. 7, 07.2014, p. 715-721.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo

AU - O'Brien, Christine M.

AU - Vargis, Elizabeth

AU - Paria, Bibhash C.

AU - Bennett, Kelly A.

AU - Mahadevan-Jansen, Anita

AU - Reese, Jeff

PY - 2014/7

Y1 - 2014/7

N2 - The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods. Conclusion Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.

AB - The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods. Conclusion Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.

KW - Cervical remodelling

KW - Cervix

KW - Parturition

KW - Pregnancy

KW - Preterm birth

UR - http://www.scopus.com/inward/record.url?scp=84902204435&partnerID=8YFLogxK

U2 - 10.1111/apa.12630

DO - 10.1111/apa.12630

M3 - Review article

C2 - 24628401

AN - SCOPUS:84902204435

VL - 103

SP - 715

EP - 721

JO - Acta Paediatrica, International Journal of Paediatrics

JF - Acta Paediatrica, International Journal of Paediatrics

SN - 0803-5253

IS - 7

ER -

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this