Raman-shifted alexandrite laser for soft tissue ablation in the 6- to 7-μm wavelength range

John Kozub, Borislav Ivanov, Aroshan Jayasinghe, Ratna Prasad, Jin Shen, Marc Klosner, Donald Heller, Marcus Mendenhall, David W. Piston, Karen Joos, M. Shane Hutson

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Prior work with free-electron lasers (FELs) showed that wavelengths in the 6- to 7-μm range could ablate soft tissues efficiently with little collateral damage; however, FELs proved too costly and too complex for widespread surgical use. Several alternative 6- to 7-μm laser systems have demonstrated the ability to cut soft tissues cleanly, but at rates that were much too low for surgical applications. Here, we present initial results with a Raman-shifted, pulsed alexandrite laser that is tunable from 6 to 7 μm and cuts soft tissues cleanly-approximately 15 μm of thermal damage surrounding ablation craters in cornea-and does so with volumetric ablation rates of 2-5 × 10-3 mm3/s. These rates are comparable to those attained in prior successful surgical trials using the FEL for optic nerve sheath fenestration.

Original languageEnglish
Pages (from-to)1275-1281
Number of pages7
JournalBiomedical Optics Express
Issue number5
StatePublished - May 1 2011


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