Radiotherapy plus Chemotherapy for Head and Neck Cancer

David A.l. Morgan, William M. Mendenhall, James T. Parsons, Jeff Michalski, Bahman Emami, Marco Merlano, Marco Benasso, Renzo Corvo

Research output: Contribution to journalLetterpeer-review

3 Scopus citations


To the Editor: In a randomized, controlled trial, Merlano et al. (Oct. 15 issue)1 present data showing improved overall survival and progression-free survival among patients with advanced head and neck cancer treated by alternating radiotherapy and chemotherapy as compared with radiotherapy alone. Before this finding can be regarded as proof that combined treatment is superior to radiotherapy alone, an explanation of why the patients treated only with radiotherapy fared so badly is essential. Published data suggest that radiotherapy is capable of giving much better results, even in patients with advanced lesions. Merlano et al. do not directly compare data on…

Original languageEnglish
Pages (from-to)579-580
Number of pages2
JournalNew England Journal of Medicine
Issue number8
StatePublished - Feb 25 1993


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