Radiosurgery for renal tumors

Although conventional EBRT has a limited role in the treatment of renal lesions, the story may be very different for stereotactic radiosurgery (SRS), or stereotactic body radiotherapy (SBRT). These approaches involve the stereotactic delivery, in one or a few fractions, of high radiation doses to limited treatment volumes, with a steep dose fall-off outside the treated region. The goal is the complete ablation of tissue. In this chapter we describe this approach to noninvasive in situ ablation of renal and adrenal lesions and review clinical findings to date. The chapter follows from and expands upon a recent review published by the authors (Vricella et al. [1]).