We describe a patient with extra-adrenal pheochmmocytoma and high plasma norepinephrine levels. Radionuclide images of this patient obtained using 18F-fluorodeoxyglucose and 123I-metaiodobenzylguanidine revealed bilateral tracer accumulation in the shoulder and lower neck. The regions of radiotracer uptake corresponded to the location of human brown adipose tissue (BAT). Excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This study showed that radionuclide imaging can noninvasively visualize human BAT in terms of metabolic and functional activity.
|Number of pages||3|
|Journal||Experimental and Clinical Endocrinology and Diabetes|
|State||Published - Nov 1 2004|
- Positron emission tomography (PET)
- Radionuclide imaging