Abstract
A comparison of several reported methods for detection and quantitation of left to right shunts by radionuclides was performed in 50 children. Count ratio (C2/C1) techniques were compared with the exponential extrapolation and gamma function area ratio techniques. C2/C1 ratios accurately detected shunts and could reliably separate shunts from normals, but there was a high rate of false positives in children with valvular heart disease. The area ratio methods provided more accurate shunt quantitation and a better separation of patients with valvular heart disease than did the C2/C1 ratio. The gamma function method showed a higher correlation with oximetry than the exponential method, but the difference was not statistically significant. For accurate shunt quantitation and a reliable separation of patients with valvular heart disease from those with shunts, area ratio calculations are preferable to the C2/C1 ratio.
Original language | English |
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Pages (from-to) | 1136-1143 |
Number of pages | 8 |
Journal | Unknown Journal |
Volume | 51 |
Issue number | 6 |
DOIs | |
State | Published - 1975 |