TY - JOUR
T1 - Radiographic and Clinical Evidence for Osteoarthritis at Medium-Term Follow-up after Arthroscopic Partial Medial Meniscectomy
AU - Lamplot, Joseph D.
AU - Tompkins, William P.
AU - Friedman, Michael V.
AU - Nguyen, Joseph T.
AU - Rai, Muhammad Farooq
AU - Brophy, Robert H.
N1 - Funding Information:
Roughly half of APMM patients will have incident radiographic OA within 6 years of APMM, and this risk increases with obesity. Females and patients with incident radiographic OA are more likely to meet clinical thresholds for OA. meniscectomy osteoarthritis knee pain Orthopaedic Research and Education Foundation (OREF) Resident Clinician Scientist Training Grant 18-014 edited-state corrected-proof typesetter ts1 Acknowledgments and Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Orthopaedic Research and Education Foundation (OREF) Resident Clinician Scientist Training Grant (grant number 18-014). Declaration of Conflicting Interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Ethical Approval This study was approved by the Washington University Institutional Review Board (IRB #201509165). Informed Consent Written and signed informed consent was obtained from all study participants. Trial Registration Not applicable. ORCID iDs Muhammad Farooq Rai https://orcid.org/0000-0003-4826-4331 Robert H. Brophy https://orcid.org/0000-0002-2912-8265
Publisher Copyright:
© The Author(s) 2019.
PY - 2021/12
Y1 - 2021/12
N2 - Objective: The purpose of this study is to assess if incident radiographic osteoarthritis (OA) is associated with clinical OA symptoms at midterm follow-up after arthroscopic partial medial meniscectomy (APMM). Design: A total of 44 patients (43% females, mean age 50.1 ± 2.8 years, minimum 5.6-year follow-up) with isolated medial meniscal tears and no-to-mild preoperative radiographic OA underwent APMM. Incident radiographic OA was assessed using the modified Kellgren-Lawrence (K-L) classification. Patients completed the Knee Injury and Osteoarthritis Outcomes Score (KOOS), and subscale thresholds for assessment of a symptomatic knee (KOOS OA criteria) and for Patient non-Acceptable Symptom State (PASS-N) following anterior cruciate ligament reconstruction (ACL-R) were calculated. Results: Incident medial compartment OA occurred in 50% of patients. Morbidly obese patients (body mass index ≥35 kg/m2) were more likely to demonstrate incident radiographic OA (100% vs. 41%, P = 0.002). Forty-three percent of patients met KOOS OA criteria, while 77% were PASS-N. Females were more likely to meet KOOS OA criteria (73% vs. 21%, P = 0.009). Patients with incident radiographic OA in any compartment were more likely than those without radiographic OA to meet KOOS OA criteria (71% vs. 17%, P = 0.008). Patients with preoperative K-L grade 2 changes in any compartment were more likely to meet KOOS OA criteria than those without K-L grade 2 changes in any compartment (83% vs. 35%, P = 0.037). Conclusions: Roughly half of APMM patients will have incident radiographic OA within 6 years of APMM, and this risk increases with obesity. Females and patients with incident radiographic OA are more likely to meet clinical thresholds for OA.
AB - Objective: The purpose of this study is to assess if incident radiographic osteoarthritis (OA) is associated with clinical OA symptoms at midterm follow-up after arthroscopic partial medial meniscectomy (APMM). Design: A total of 44 patients (43% females, mean age 50.1 ± 2.8 years, minimum 5.6-year follow-up) with isolated medial meniscal tears and no-to-mild preoperative radiographic OA underwent APMM. Incident radiographic OA was assessed using the modified Kellgren-Lawrence (K-L) classification. Patients completed the Knee Injury and Osteoarthritis Outcomes Score (KOOS), and subscale thresholds for assessment of a symptomatic knee (KOOS OA criteria) and for Patient non-Acceptable Symptom State (PASS-N) following anterior cruciate ligament reconstruction (ACL-R) were calculated. Results: Incident medial compartment OA occurred in 50% of patients. Morbidly obese patients (body mass index ≥35 kg/m2) were more likely to demonstrate incident radiographic OA (100% vs. 41%, P = 0.002). Forty-three percent of patients met KOOS OA criteria, while 77% were PASS-N. Females were more likely to meet KOOS OA criteria (73% vs. 21%, P = 0.009). Patients with incident radiographic OA in any compartment were more likely than those without radiographic OA to meet KOOS OA criteria (71% vs. 17%, P = 0.008). Patients with preoperative K-L grade 2 changes in any compartment were more likely to meet KOOS OA criteria than those without K-L grade 2 changes in any compartment (83% vs. 35%, P = 0.037). Conclusions: Roughly half of APMM patients will have incident radiographic OA within 6 years of APMM, and this risk increases with obesity. Females and patients with incident radiographic OA are more likely to meet clinical thresholds for OA.
KW - knee pain
KW - meniscectomy
KW - osteoarthritis
UR - http://www.scopus.com/inward/record.url?scp=85077192667&partnerID=8YFLogxK
U2 - 10.1177/1947603519892315
DO - 10.1177/1947603519892315
M3 - Article
C2 - 31829031
AN - SCOPUS:85077192667
SN - 1947-6035
VL - 13
SP - 588S-594S
JO - Cartilage
JF - Cartilage
IS - 1_suppl
ER -