Radiation therapy for infants with cancer

Colette J. Shen, Stephanie M. Perkins, Julie A. Bradley, Anita Mahajan, Karen J. Marcus

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The clinical outcomes for infants with malignant tumors are often worse than older children due to a combination of more biologically aggressive disease in some cases, and increased toxicity—or deintensification of therapies due to concern for toxicity—in others. Especially in infants and very young children, finding the appropriate balance between maximizing treatment efficacy while minimizing toxicity—in particular late side effects—is crucial. We review here the management of malignant tumors in infants and very young children, focusing on central nervous system (CNS) malignancies and rhabdomyosarcoma.

Original languageEnglish
Article numbere28700
JournalPediatric Blood and Cancer
Issue numberS2
StatePublished - May 2021


  • brain tumors
  • cancer
  • chemotherapy
  • infants
  • late effects
  • radiation therapy
  • rhabdomyosarcoma
  • surgery


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