TY - JOUR
T1 - Radiation Therapy for Advanced-Stage Hodgkin Lymphoma
AU - Lockney, Natalie A.
AU - Yang, Joanna C.
N1 - Publisher Copyright:
© 2020 The Authors
PY - 2020/9/1
Y1 - 2020/9/1
N2 - The backbone of treatment for patients with advanced-stage Hodgkin lymphoma is systemic therapy. The use of radiation therapy as a component of combined-modality treatment in this setting is controversial. In this review, we describe the data in support of and against the use of radiation therapy for stage III and IV Hodgkin lymphoma. Specifically, we review the data for the use of radiation therapy in the consolidation and partial-response settings, including for patients with initial bulky disease. We also discuss the use of radiation therapy in the era of more modern systemic therapies, including checkpoint inhibitors and brentuximab vedotin.
AB - The backbone of treatment for patients with advanced-stage Hodgkin lymphoma is systemic therapy. The use of radiation therapy as a component of combined-modality treatment in this setting is controversial. In this review, we describe the data in support of and against the use of radiation therapy for stage III and IV Hodgkin lymphoma. Specifically, we review the data for the use of radiation therapy in the consolidation and partial-response settings, including for patients with initial bulky disease. We also discuss the use of radiation therapy in the era of more modern systemic therapies, including checkpoint inhibitors and brentuximab vedotin.
UR - http://www.scopus.com/inward/record.url?scp=85087964542&partnerID=8YFLogxK
U2 - 10.1016/j.adro.2020.06.001
DO - 10.1016/j.adro.2020.06.001
M3 - Review article
C2 - 33083642
AN - SCOPUS:85087964542
SN - 2452-1094
VL - 5
SP - 809
EP - 816
JO - Advances in Radiation Oncology
JF - Advances in Radiation Oncology
IS - 5
ER -