TY - JOUR
T1 - Radiation injury of the lung after stereotactic body radiation therapy (SBRT) for lung cancer
T2 - A timeline and pattern of CT changes
AU - Linda, Anna
AU - Trovo, Marco
AU - Bradley, Jeffrey D.
PY - 2011/7
Y1 - 2011/7
N2 - Stereotactic body radiation therapy (SBRT) is a new radiotherapy treatment method that has been applied to the treatment of Stage I lung cancers in medically inoperable patients, with excellent clinical results. SBRT allows the delivery of a very high radiation dose to the target volume, while minimizing the dose to the adjacent normal tissues. As a consequence, CT findings after SBRT have different appearance, geographic extent and progression timeline compared to those following conventional radiation therapy for lung cancer. In particular, SBRT-induced changes are limited to the "shell" of normal tissue outside the tumor and have a complex shape. When SBRT-induced CT changes have a consolidation/mass-like appearance, the differentiation from tumor recurrence can be very difficult. An understanding of SBRT technique as it relates to the development of SBRT-induced lung injury and familiarity with the full spectrum of CT manifestations are important to facilitate diagnosis and management of lung cancer patients treated with this newly emerging radiotherapy method.
AB - Stereotactic body radiation therapy (SBRT) is a new radiotherapy treatment method that has been applied to the treatment of Stage I lung cancers in medically inoperable patients, with excellent clinical results. SBRT allows the delivery of a very high radiation dose to the target volume, while minimizing the dose to the adjacent normal tissues. As a consequence, CT findings after SBRT have different appearance, geographic extent and progression timeline compared to those following conventional radiation therapy for lung cancer. In particular, SBRT-induced changes are limited to the "shell" of normal tissue outside the tumor and have a complex shape. When SBRT-induced CT changes have a consolidation/mass-like appearance, the differentiation from tumor recurrence can be very difficult. An understanding of SBRT technique as it relates to the development of SBRT-induced lung injury and familiarity with the full spectrum of CT manifestations are important to facilitate diagnosis and management of lung cancer patients treated with this newly emerging radiotherapy method.
KW - Computed tomography
KW - Radiation fibrosis
KW - Radiation pneumonitis
KW - SBRT
KW - Stereotactic radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=79958765549&partnerID=8YFLogxK
U2 - 10.1016/j.ejrad.2009.10.029
DO - 10.1016/j.ejrad.2009.10.029
M3 - Review article
C2 - 19954913
AN - SCOPUS:79958765549
SN - 0720-048X
VL - 79
SP - 147
EP - 154
JO - European Journal of Radiology
JF - European Journal of Radiology
IS - 1
ER -