Radiation esophagitis: Predictive factors and preventive strategies

Jeffrey Bradley, Benjamin Movsas

    Research output: Contribution to journalArticlepeer-review

    47 Scopus citations

    Abstract

    Radiation esophagitis remains the primary dose-limiting acute toxicity in the radiotherapeutic management of thoracic neoplasms. Improved understanding of this toxicity will facilitate dose escalation and enhancement of the therapeutic ratio. This article reviews the predictive factors and preventive strategies for radiation esophagitis. In particular, clinical and dosimetric studies predicting the risk of radiation esophagitis are analyzed. The critical impact of chemotherapy on radiation esophagitis is characterized. Preventive strategies to minimize this toxicity also are explored. Overall, this article reviews the current understanding of radiation toxicity for the esophagus.

    Original languageEnglish
    Pages (from-to)280-286
    Number of pages7
    JournalSeminars in Radiation Oncology
    Volume14
    Issue number4
    DOIs
    StatePublished - Oct 2004

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