Radiation esophagitis: Predictive factors and preventive strategies

Jeffrey Bradley, Benjamin Movsas

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Radiation esophagitis remains the primary dose-limiting acute toxicity in the radiotherapeutic management of thoracic neoplasms. Improved understanding of this toxicity will facilitate dose escalation and enhancement of the therapeutic ratio. This article reviews the predictive factors and preventive strategies for radiation esophagitis. In particular, clinical and dosimetric studies predicting the risk of radiation esophagitis are analyzed. The critical impact of chemotherapy on radiation esophagitis is characterized. Preventive strategies to minimize this toxicity also are explored. Overall, this article reviews the current understanding of radiation toxicity for the esophagus.

Original languageEnglish
Pages (from-to)280-286
Number of pages7
JournalSeminars in Radiation Oncology
Volume14
Issue number4
DOIs
StatePublished - Oct 2004

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