Radiation Dose-Volume Effects in the Lung

Lawrence B. Marks; Soren M. Bentzen; Joseph O. Deasy; Feng Ming (Spring) Kong; Jeffrey D. Bradley; Ivan S. Vogelius; Issam El Naqa; Jessica L. Hubbs; Joos V. Lebesque; Robert D. Timmerman; Mary K. Martel; Andrew Jackson

doi:10.1016/j.ijrobp.2009.06.091

Radiation Dose-Volume Effects in the Lung

Lawrence B. Marks, Soren M. Bentzen, Joseph O. Deasy, Feng Ming (Spring) Kong, Jeffrey D. Bradley, Ivan S. Vogelius, Issam El Naqa, Jessica L. Hubbs, Joos V. Lebesque, Robert D. Timmerman, Mary K. Martel, Andrew Jackson

Research output: Contribution to journal › Article › peer-review

853 Scopus citations

Abstract

The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.

Original language	English
Pages (from-to)	S70-S76
Journal	International Journal of Radiation Oncology Biology Physics
Volume	76
Issue number	3 SUPPL.
DOIs	https://doi.org/10.1016/j.ijrobp.2009.06.091
State	Published - Mar 1 2010

Keywords

Lung injury
Pneumonitis
QUANTEC
Radiation

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10.1016/j.ijrobp.2009.06.091

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title = "Radiation Dose-Volume Effects in the Lung",

abstract = "The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold {"}tolerance dose-volume{"} levels. There are strong volume and fractionation effects.",

keywords = "Lung injury, Pneumonitis, QUANTEC, Radiation",

author = "Marks, {Lawrence B.} and Bentzen, {Soren M.} and Deasy, {Joseph O.} and Kong, {Feng Ming (Spring)} and Bradley, {Jeffrey D.} and Vogelius, {Ivan S.} and {El Naqa}, Issam and Hubbs, {Jessica L.} and Lebesque, {Joos V.} and Timmerman, {Robert D.} and Martel, {Mary K.} and Andrew Jackson",

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doi = "10.1016/j.ijrobp.2009.06.091",

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T1 - Radiation Dose-Volume Effects in the Lung

AU - Marks, Lawrence B.

AU - Bentzen, Soren M.

AU - Deasy, Joseph O.

AU - Kong, Feng Ming (Spring)

AU - Bradley, Jeffrey D.

AU - Vogelius, Ivan S.

AU - El Naqa, Issam

AU - Hubbs, Jessica L.

AU - Lebesque, Joos V.

AU - Timmerman, Robert D.

AU - Martel, Mary K.

AU - Jackson, Andrew

PY - 2010/3/1

Y1 - 2010/3/1

N2 - The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.

AB - The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.

KW - Lung injury

KW - Pneumonitis

KW - QUANTEC

KW - Radiation

UR - http://www.scopus.com/inward/record.url?scp=76449119210&partnerID=8YFLogxK

U2 - 10.1016/j.ijrobp.2009.06.091

DO - 10.1016/j.ijrobp.2009.06.091

M3 - Article

C2 - 20171521

AN - SCOPUS:76449119210

SN - 0360-3016

VL - 76

SP - S70-S76

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

IS - 3 SUPPL.

ER -

Radiation Dose-Volume Effects in the Lung

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Keywords

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