TY - JOUR
T1 - Racial differences in gait mechanics associated with knee osteoarthritis
AU - Sims, Ershela L.
AU - Keefe, Francis J.
AU - Kraus, Virginia B.
AU - Guilak, Farshid
AU - Queen, Robin M.
AU - Schmitt, Daniel
N1 - Funding Information:
The authors would like to thank Maarryy BBeetthh NNeebbeell,, MMaatthheeww WWiilllliiaamms Paul Riordan, Dr. Sandra Stiinnnneetttt,, aanndd DDrr.. JJeennnniiffeerr PPeellllss ffoorr tthheir thoughtful contributions to this work. This research was supported by NIH grants AR50245 and AG15768.
PY - 2009/12
Y1 - 2009/12
N2 - Background and aims: This study examines racial differences in gait mechanics in persons with knee osteoarthritis and the influence of anthropometrics, educational level, radiographic disease severity (rOA), and self-report measures of pain and disability on racial differences in gait. Methods: One hundred seventy five (64 black and 111 white) adults with radiographic knee OA were tested. 3-D kinematic and kinetic data were collected while subjects walked at two self-selected speeds (normal and fast). Anthropometric data, radiographic level of OA, and self-report measures of pain and disability were also collected. Gait patterns were compared across groups and within groups. Results: Black and white subjects did not differ significantly in radiographic OA. However, blacks walked significantly more slowly when asked to walk fast. At the normal speed, blacks had a smaller knee range of motion and loading rate than whites. Blacks also took longer to reach their peak maximum ground reaction force than whites. Within black subjects variations in gait mechanics were primarily explained by BMI, rOA, self-reported psychological disability, and pain self-efficacy. In white subjects, variations in gait mechanics were primarily explained by weight, age, velocity, psychological disability, and self-efficacy. Conclusions: Blacks in this study had a pattern of gait mechanics generally associated with high levels of osteoarthritis, though they did not differ significantly in rOA from whites. The variability in gait patterns exhibited by blacks was most strongly related to variance in walking speed, anthropometrics, and perceived physical ability. Taken together, these results suggest that race is an important factor that must be considered in the treatment and study of osteoarthritis.
AB - Background and aims: This study examines racial differences in gait mechanics in persons with knee osteoarthritis and the influence of anthropometrics, educational level, radiographic disease severity (rOA), and self-report measures of pain and disability on racial differences in gait. Methods: One hundred seventy five (64 black and 111 white) adults with radiographic knee OA were tested. 3-D kinematic and kinetic data were collected while subjects walked at two self-selected speeds (normal and fast). Anthropometric data, radiographic level of OA, and self-report measures of pain and disability were also collected. Gait patterns were compared across groups and within groups. Results: Black and white subjects did not differ significantly in radiographic OA. However, blacks walked significantly more slowly when asked to walk fast. At the normal speed, blacks had a smaller knee range of motion and loading rate than whites. Blacks also took longer to reach their peak maximum ground reaction force than whites. Within black subjects variations in gait mechanics were primarily explained by BMI, rOA, self-reported psychological disability, and pain self-efficacy. In white subjects, variations in gait mechanics were primarily explained by weight, age, velocity, psychological disability, and self-efficacy. Conclusions: Blacks in this study had a pattern of gait mechanics generally associated with high levels of osteoarthritis, though they did not differ significantly in rOA from whites. The variability in gait patterns exhibited by blacks was most strongly related to variance in walking speed, anthropometrics, and perceived physical ability. Taken together, these results suggest that race is an important factor that must be considered in the treatment and study of osteoarthritis.
KW - Disability
KW - Gait
KW - Osteoarthritis
KW - Racial differences
UR - http://www.scopus.com/inward/record.url?scp=77649260463&partnerID=8YFLogxK
U2 - 10.1007/BF03327442
DO - 10.1007/BF03327442
M3 - Article
C2 - 20154517
AN - SCOPUS:77649260463
SN - 1594-0667
VL - 21
SP - 463
EP - 469
JO - Aging Clinical and Experimental Research
JF - Aging Clinical and Experimental Research
IS - 6
ER -