Quantitative ultrasonic imaging: Tissue characterization and instantaneous quantification of cardiac function

Julio E. Pérez, James G. Miller, Samuel A. Wickline, Mark R. Holland, Alan D. Waggoner, Benico Barzilai, Burton E. Sobel

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Quantitative myocardial tissue characterization is being developed to complement and expand conventional echocardiography by delineating the physical state of myocardium under diverse pathophysiologic conditions. Real-time quantitative integrated backscatter imaging has already been applied to patients with ischemic heart disease, hypertrophic cardiomyopathy, and cardiac allograft rejection in clinical investigations performed in the United States, Europe, and Japan. A recently introduced modification of imaging processing algorithms employed for characterization of tissue facilitates automatic detection of endocardial-blood interfaces and on-line quantification of ventricular size and function. Further progress and anticipated developments in quantitative ultrasonic imaging will undoubtedly augment the clinical applications of tissue characterizations based on myocardial integrated backscatter for improved diagnosis, elucidation of pathophysiology, and assessment of cardiac function.

Original languageEnglish
Pages (from-to)H104-H111
JournalThe American journal of cardiology
Volume69
Issue number20
DOIs
StatePublished - Jun 18 1992

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