Quantitative evaluation of registration methods for atlas-based Diffuse Optical Tomography

Xue Wu, Adam T. Eggebrecht, Joseph P. Culver, Yuxuan Zhan, Hector Basevi, Hamid Dehghani

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


In Diffuse Optical Tomography (DOT), an atlas-based model can be used as an alternative to a subject-specific anatomical model for recovery of brain activity. The main step of the generation of atlas-based subject model is the registration of atlas model to the subject head. The accuracy of the DOT then relies on the accuracy of registration method. In this work, 11 registration methods are quantitatively evaluated. The registration method with EEG 10/20 systems with 19 landmarks and non-iterative point to point algorithm provides approximately 1.4 mm surface error and is considered as the most efficient registration method.

Original languageEnglish
Title of host publicationDiffuse Optical Imaging IV
StatePublished - Aug 12 2013
EventDiffuse Optical Imaging IV - Munich, Germany
Duration: May 12 2013May 14 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceDiffuse Optical Imaging IV


  • Atlas-based model
  • Diffuse optical tomography
  • Registration


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