Quantitative assessment of atrial regional function using motion estimation computed tomography

Hiroshi Ashikaga, Jochen Cammin, Qiulin Tang, Karly Knudsen, Yuko Inoue, Elliot K. Fishman, Katsuyuki Taguchi

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objectives: We validated a novel image-based motion estimation computed tomographic (CT) technique (iME) to quantify atrial regional function in swine in vivo.

Materials and Methods: Domestic swine (n = 8) underwent CT scan with intravenous contrast before and after median sternotomy where 15 to 30 glass beads were sutured to the atria to calculate the motion estimation error. Four-dimensional motion vector field was estimated using iME. Area change ratio (%AC) was calculated over the atrial endocardium to assess the surface deformation.

Results: The error between the measured and the calculated coordinates based onmotion vector fieldwas 0.76 ± 0.43mm. The%ACwas regionally heterogeneous. The %AC time course was significantly different between the right and the left atriums (P < 0.001) as well as between the right atrial appendage and the right atrial chamber (P = 0.004).

Conclusions: Quantitative assessment of atrial regional function using iME is highly accurate. Image-based motion estimation computed tomographic (CT) technique can quantify subtle regional dysfunction that is not apparent in global functional indices such as ejection fraction.

Original languageEnglish
Pages (from-to)773-778
Number of pages6
JournalJournal of computer assisted tomography
Volume38
Issue number5
DOIs
StatePublished - 2014

Keywords

  • Atrial function
  • Cardiac CT
  • Image processing
  • Regional function

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