Quantification of protein-ligand interactions in solution by hydrogen/deuterium exchange (PLIMSTEX)

Mei M. Zhu, David Hambly, Michael L. Gross

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations
Original languageEnglish
Title of host publicationApplications in Drug Discovery
PublisherWiley Blackwell
Pages339-375
Number of pages37
Volume36
ISBN (Electronic)9783527610907
ISBN (Print)9783527314560
DOIs
StatePublished - Jan 1 2007

Keywords

  • Applications of PLIMSTEX; determination of association constant (Ka)
  • Fast photochemical oxidation of proteins
  • Fast radical footprinting for protein-ligand interaction analysis
  • PLIMSTEX method
  • Quantification of protein-ligand interactions in solution by hydrogen/deuterium exchange (PLIMSTEX)
  • Stoichiometry (n) and protection (ΔDi); features of PLIMSTEX

Cite this