@inproceedings{cd9bb424545e4b74bfc61c19b0ca38e8,
title = "Quantification of photoacoustic microscopy images for ovarian cancer detection",
abstract = "In this paper, human ovarian tissues with malignant and benign features were imaged ex vivo by using an opticalresolution photoacoustic microscopy (OR-PAM) system. Several features were quantitatively extracted from PAM images to describe photoacoustic signal distributions and fluctuations. 106 PAM images from 18 human ovaries were classified by applying those extracted features to a logistic prediction model. 57 images from 9 ovaries were used as a training set to train the logistic model, and 49 images from another 9 ovaries were used to test our prediction model. We assumed that if one image from one malignant ovary was classified as malignant, it is sufficient to classify this ovary as malignant. For the training set, we achieved 100\% sensitivity and 83.3\% specificity; for testing set, we achieved 100\% sensitivity and 66.7\% specificity. These preliminary results demonstrate that PAM could be extremely valuable in assisting and guiding surgeons for in vivo evaluation of ovarian tissue.",
keywords = "Blood vessel, Logistic model, Ovarian cancer, Photoacoustic microscopy",
author = "Tianheng Wang and Yi Yang and Umar Alqasemi and Kumavor, \{Patrick D.\} and Xiaohong Wang and Melinda Sanders and Molly Brewer and Quing Zhu",
year = "2014",
doi = "10.1117/12.2036129",
language = "English",
isbn = "9780819498564",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2014 ; Conference date: 02-02-2014 Through 05-02-2014",
}