Quality of life in patients 2 years and 3 years post lung volume reduction surgery

Mary S. Pohl, R. D. Yusen, G. E. Davis, S. S. Lefrak, J. D. Cooper

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose: To analyze if survivors with long term followup after Lung Volume Reduction Surgery (LVRS) continue to have improved Quality of Life (QOL) compared to their preoperative QOL. Methods: Patients with emphysema were evaluated for their QOL preoperatively and at two and three years postoperatively using the Medical Outcomes Survey Short Form 36 (MOS) and the Nottingham Health Profile (NHP). A cohort of 103 patients (91% follow-up) was studied who had preop and two year data available and another cohort of 47 (85%) follow-ups had preop, 2 yr., and 3 yr. data. Either the Sign test, F Test, or the paired two-tailed t-test was used to analyze between time period data. FEV1, oxygen usage, and the Modified Medical Research Council Dyspnea Scale (MRC) were also studied. Results: For both cohorts of patients there was a significant increase (p<.05) in QOL on all variables at the two year time point. Those patients with 3 year data (n=47) had a slight, but non-significant (p=ns), decline in their QOL from the 2 to 3 year period. The 3 yr. cohort is listed in the table: Test Preop] 2 yrs 3 yrs FEV1(%pred) .74(26%) 1.0(37%) .98(35%) O2 Rest 46% 16% 33% O2 Exer 88% 56% 68% MRC 2.8 1.5 2.0 Conclusions: Of those patients with available QOL data there was a significant increase in all areas to two years with a corresponding improvement in their FEV1, oxygen status, and MRC. This improvement declines somewhat in the third year but remains significantly improved compared with the pre-op status. Clinical Implications: LVRS appears to improve patients QOL and functional status for at least 3 years.

Original languageEnglish
Pages (from-to)351S-352S
Issue number4 SUPPL.
StatePublished - Oct 1 1998


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