Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1β-converting enzyme inhibitor

R. E. Dolle; C. V.C. Prasad; C. P. Prouty; J. M. Salvino; M. M.A. Awad; S. J. Schmidt; D. Hoyer; T. M. Ross; T. L. Graybill; G. J. Speier; J. Uhl; B. E. Miller; C. T. Helaszek; M. A. Ator

doi:10.1021/jm9701637

Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor

R. E. Dolle, C. V.C. Prasad, C. P. Prouty, J. M. Salvino, M. M.A. Awad, S. J. Schmidt, D. Hoyer, T. M. Ross, T. L. Graybill, G. J. Speier, J. Uhl, B. E. Miller, C. T. Helaszek, M. A. Ator

Center for Drug Discovery

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51 Scopus citations

Original language	English
Pages (from-to)	1941-1946
Number of pages	6
Journal	Journal of Medicinal Chemistry
Volume	40
Issue number	13
DOIs	https://doi.org/10.1021/jm9701637
State	Published - 1997

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10.1021/jm9701637

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Dolle, R. E., Prasad, C. V. C., Prouty, C. P., Salvino, J. M., Awad, M. M. A., Schmidt, S. J., Hoyer, D., Ross, T. M., Graybill, T. L., Speier, G. J., Uhl, J., Miller, B. E., Helaszek, C. T., & Ator, M. A. (1997). Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor. Journal of Medicinal Chemistry, 40(13), 1941-1946. https://doi.org/10.1021/jm9701637

Dolle, R. E. ; Prasad, C. V.C. ; Prouty, C. P. ; Salvino, J. M. ; Awad, M. M.A. ; Schmidt, S. J. ; Hoyer, D. ; Ross, T. M. ; Graybill, T. L. ; Speier, G. J. ; Uhl, J. ; Miller, B. E. ; Helaszek, C. T. ; Ator, M. A. / Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor. In: Journal of Medicinal Chemistry. 1997 ; Vol. 40, No. 13. pp. 1941-1946.

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title = "Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1β-converting enzyme inhibitor",

author = "Dolle, {R. E.} and Prasad, {C. V.C.} and Prouty, {C. P.} and Salvino, {J. M.} and Awad, {M. M.A.} and Schmidt, {S. J.} and D. Hoyer and Ross, {T. M.} and Graybill, {T. L.} and Speier, {G. J.} and J. Uhl and Miller, {B. E.} and Helaszek, {C. T.} and Ator, {M. A.}",

year = "1997",

doi = "10.1021/jm9701637",

language = "English",

volume = "40",

pages = "1941--1946",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

number = "13",

}

Dolle, RE, Prasad, CVC, Prouty, CP, Salvino, JM, Awad, MMA, Schmidt, SJ, Hoyer, D, Ross, TM, Graybill, TL, Speier, GJ, Uhl, J, Miller, BE, Helaszek, CT & Ator, MA 1997, 'Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor', Journal of Medicinal Chemistry, vol. 40, no. 13, pp. 1941-1946. https://doi.org/10.1021/jm9701637

Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor. / Dolle, R. E.; Prasad, C. V.C.; Prouty, C. P.; Salvino, J. M.; Awad, M. M.A.; Schmidt, S. J.; Hoyer, D.; Ross, T. M.; Graybill, T. L.; Speier, G. J.; Uhl, J.; Miller, B. E.; Helaszek, C. T.; Ator, M. A.

In: Journal of Medicinal Chemistry, Vol. 40, No. 13, 1997, p. 1941-1946.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1β-converting enzyme inhibitor

AU - Dolle, R. E.

AU - Prasad, C. V.C.

AU - Prouty, C. P.

AU - Salvino, J. M.

AU - Awad, M. M.A.

AU - Schmidt, S. J.

AU - Hoyer, D.

AU - Ross, T. M.

AU - Graybill, T. L.

AU - Speier, G. J.

AU - Uhl, J.

AU - Miller, B. E.

AU - Helaszek, C. T.

AU - Ator, M. A.

PY - 1997

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AN - SCOPUS:17144451277

VL - 40

SP - 1941

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JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

IS - 13

ER -

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1β-converting enzyme inhibitor

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Pyridazinodiazepines as a high-affinity, P₂-P₃ peptidomimetic class of interleukin-1β-converting enzyme inhibitor