PXR: A New Player in Atopic Dermatitis

Landon K. Oetjen; Anna M. Trier; Brian S. Kim

doi:10.1016/j.jid.2017.08.002

PXR: A New Player in Atopic Dermatitis

Landon K. Oetjen
, Anna M. Trier
, Brian S. Kim

Research output: Contribution to journal › Comment/debate

5 Scopus citations

Abstract

Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.

Original language	English
Pages (from-to)	8-10
Number of pages	3
Journal	Journal of Investigative Dermatology
Volume	138
Issue number	1
DOIs	https://doi.org/10.1016/j.jid.2017.08.002
State	Published - Jan 2018

Access to Document

10.1016/j.jid.2017.08.002

Cite this

@article{0ba0558c038d43b999b6dc66824a91c9,

title = "PXR: A New Player in Atopic Dermatitis",

abstract = "Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.",

author = "Oetjen, \{Landon K.\} and Trier, \{Anna M.\} and Kim, \{Brian S.\}",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors",

year = "2018",

month = jan,

doi = "10.1016/j.jid.2017.08.002",

language = "English",

volume = "138",

pages = "8--10",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

number = "1",

}

TY - JOUR

T1 - PXR

T2 - A New Player in Atopic Dermatitis

AU - Oetjen, Landon K.

AU - Trier, Anna M.

AU - Kim, Brian S.

PY - 2018/1

Y1 - 2018/1

N2 - Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.

AB - Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.

UR - https://www.scopus.com/pages/publications/85039941718

U2 - 10.1016/j.jid.2017.08.002

DO - 10.1016/j.jid.2017.08.002

M3 - Comment/debate

C2 - 29273149

AN - SCOPUS:85039941718

SN - 0022-202X

VL - 138

SP - 8

EP - 10

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 1

ER -

PXR: A New Player in Atopic Dermatitis

Abstract

Access to Document

Other files and links

Fingerprint

Cite this