Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.

Original languageEnglish
Pages (from-to)8-10
Number of pages3
JournalJournal of Investigative Dermatology
Issue number1
StatePublished - Jan 2018


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