TY - JOUR
T1 - Pulmonary pleomorphic carcinoma after malignant lymphoma remission
T2 - A case report
AU - Takahashi, Tsuyoshi
AU - Kurihara, Masako
AU - Nogimura, Hiroshi
AU - Kobayashi, Ryo
PY - 2015/2/1
Y1 - 2015/2/1
N2 - A 78-year-old woman diagnosed with diffuse large B-cell lymphoma in the left supra-pharynx and left supraclavicular lymph nodes showed complete remission after undergoing radiation therapy and chemotherapy in September 2006. In September 2008, during a routine follow-up evaluation for the malignant lymphoma, elevated levels of soluble interleukin-2 receptor were detected in the serum; moreover, computed tomography revealed a nodule in the right middle lobe and mediastinal lymphadenopathy. Recurrence of the malignant lymphoma was suspected, and the patient underwent a chemotherapy regimen of rituximab combined with pirarubicin, cyclophosphamide, vincristine, and prednisolone. However, her general condition deteriorated and she died. The postmortem autopsy revealed a pulmonary pleomorphic carcinoma with metastases to the mediastinal lymph nodes. However, there was no evidence of malignant lymphoma recurrence. We encountered a case of pulmonary pleomorphic carcinoma that occurred after the remission of a malignant lymphoma.
AB - A 78-year-old woman diagnosed with diffuse large B-cell lymphoma in the left supra-pharynx and left supraclavicular lymph nodes showed complete remission after undergoing radiation therapy and chemotherapy in September 2006. In September 2008, during a routine follow-up evaluation for the malignant lymphoma, elevated levels of soluble interleukin-2 receptor were detected in the serum; moreover, computed tomography revealed a nodule in the right middle lobe and mediastinal lymphadenopathy. Recurrence of the malignant lymphoma was suspected, and the patient underwent a chemotherapy regimen of rituximab combined with pirarubicin, cyclophosphamide, vincristine, and prednisolone. However, her general condition deteriorated and she died. The postmortem autopsy revealed a pulmonary pleomorphic carcinoma with metastases to the mediastinal lymph nodes. However, there was no evidence of malignant lymphoma recurrence. We encountered a case of pulmonary pleomorphic carcinoma that occurred after the remission of a malignant lymphoma.
KW - Chemotherapy
KW - Malignant lymphoma
KW - Pleomorphic carcinoma of the lung
UR - http://www.scopus.com/inward/record.url?scp=84924354714&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84924354714
SN - 0385-3667
VL - 74
SP - 226
EP - 230
JO - Japanese Journal of Chest Diseases
JF - Japanese Journal of Chest Diseases
IS - 2
ER -