Pulmonary hypertension and lung transplant in connective tissue disease-interstitial lung disease

Lana Melendres-Groves, Rodrigo Vazquez-Guillamet, Gundeep Dhillon

Research output: Contribution to journalArticlepeer-review


There is a paucity of research and a lack of necessary guidance for proper characterization of pulmonary hypertension presenting in patients with connective tissue disease and interstitial lung disease, specifically related to differentiating between WHO group 1 pulmonary arterial hypertension and WHO group 3 pulmonary hypertension due to lung disease and/or hypoxia. Without a mechanism for proper differentiation of the type of pulmonary hypertension that exists, appropriate management of this subset of individuals is particularly challenging. This review presents the pertinent research that exist regarding the intricacies of this disease state with the goal of providing improved guidance as to who may benefit from screening, diagnosis, treatment in a facility with expertise in the field, and referral for lung transplant.

Original languageEnglish
Pages (from-to)156-162
Number of pages7
JournalCurrent Respiratory Medicine Reviews
Issue number2
StatePublished - Sep 1 2015


  • Connective tissue disease
  • Interstitial lung disease
  • Lung transplant
  • Parenchymal lung disease
  • Pulmonary arterial hypertension
  • Pulmonary hypertension


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