TY - JOUR
T1 - Pulmonary artery banding in complete atrioventricular septal defect
AU - Devlin, Paul J.
AU - Jegatheeswaran, Anusha
AU - McCrindle, Brian W.
AU - Karamlou, Tara
AU - Blackstone, Eugene H.
AU - Williams, William G.
AU - DeCampli, William M.
AU - Mertens, Luc
AU - Fackoury, Cheryl T.
AU - Eghtesady, Pirooz
AU - Jacobs, Jeffrey P.
AU - Baffa, Jeanne M.
AU - Fleishman, Craig E.
AU - Dodge-Khatami, Ali
AU - Pizarro, Christian
AU - Pourmoghadam, Kamal
AU - Cohen, Meryl S.
AU - Meyer, David B.
AU - Overman, David M.
N1 - Funding Information:
Funding for Dr Devlin was provided by the Congenital Heart Surgeons' Society (CHSS) John W. Kirklin/David Ashburn Fellowship, The Hospital for Sick Children's Division of Cardiovascular Surgery, and the Ann & Robert H. Lurie Children's Hospital of Chicago's Division of Cardiovascular-Thoracic Surgery. Funding was also provided by the Ludwig Foundation and The Children's Heart Clinic, Division of Cardiovascular Surgery, The Children's Heart Clinic, Children's Hospitals and Clinics of Minnesota. The CHSS Data Center is supported financially by all CHSS institutional members.
Publisher Copyright:
© 2019 The American Association for Thoracic Surgery
PY - 2020/4
Y1 - 2020/4
N2 - Objectives: To analyze outcomes after pulmonary artery banding (PAB) in complete atrioventricular septal defect (AVSD), with a focus on surgical pathway outcome and timing, survival, and atrioventricular valve function. Methods: PAB was performed in 50 of 474 infants (11%) from 28 institutions between 2012 and 2018 at a median age of 1.1 months. The median duration of follow-up was 2.1 years. Atrioventricular valve function was assessed by review of pre-PAB and predischarge echocardiograms (median, 9 days postoperatively). Competing-risks methodology was used to analyze the risks for biventricular repair, univentricular repair, and death. Results: At 2 years, the proportions of patients who underwent biventricular repair, univentricular repair, and death were 68%, 13%, and 12%, respectively, with 8% awaiting definitive repair. After PAB, atrioventricular valve regurgitation decreased in 14 infants and increased in 10, but the distribution of regurgitation severity did not change significantly in the total cohort or subgroups. The intended management plan at PAB was deferred biventricular/univentricular decision (23 infants), 2-stage biventricular repair (24 infants), and univentricular repair (3 infants). Among the 24 infants intended for biventricular repair, 23 achieved biventricular repair and 1 died before repair. Survival at 4 years after biventricular repair among patients with previous PAB (93%) was similar to the 4-year survival of the patients who underwent primary biventricular repair (91%; n = 333). Conclusions: PAB is a successful strategy in complete AVSD to bridge to biventricular repair and has similar post-biventricular repair survival to primary biventricular repair. Changes in atrioventricular valve regurgitation after PAB were variable.
AB - Objectives: To analyze outcomes after pulmonary artery banding (PAB) in complete atrioventricular septal defect (AVSD), with a focus on surgical pathway outcome and timing, survival, and atrioventricular valve function. Methods: PAB was performed in 50 of 474 infants (11%) from 28 institutions between 2012 and 2018 at a median age of 1.1 months. The median duration of follow-up was 2.1 years. Atrioventricular valve function was assessed by review of pre-PAB and predischarge echocardiograms (median, 9 days postoperatively). Competing-risks methodology was used to analyze the risks for biventricular repair, univentricular repair, and death. Results: At 2 years, the proportions of patients who underwent biventricular repair, univentricular repair, and death were 68%, 13%, and 12%, respectively, with 8% awaiting definitive repair. After PAB, atrioventricular valve regurgitation decreased in 14 infants and increased in 10, but the distribution of regurgitation severity did not change significantly in the total cohort or subgroups. The intended management plan at PAB was deferred biventricular/univentricular decision (23 infants), 2-stage biventricular repair (24 infants), and univentricular repair (3 infants). Among the 24 infants intended for biventricular repair, 23 achieved biventricular repair and 1 died before repair. Survival at 4 years after biventricular repair among patients with previous PAB (93%) was similar to the 4-year survival of the patients who underwent primary biventricular repair (91%; n = 333). Conclusions: PAB is a successful strategy in complete AVSD to bridge to biventricular repair and has similar post-biventricular repair survival to primary biventricular repair. Changes in atrioventricular valve regurgitation after PAB were variable.
KW - AVSD
KW - complete atrioventricular septal defect
KW - pulmonary artery banding
UR - http://www.scopus.com/inward/record.url?scp=85074439996&partnerID=8YFLogxK
U2 - 10.1016/j.jtcvs.2019.09.019
DO - 10.1016/j.jtcvs.2019.09.019
M3 - Article
C2 - 31669019
AN - SCOPUS:85074439996
SN - 0022-5223
VL - 159
SP - 1493-1503.e3
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
IS - 4
ER -