TY - JOUR
T1 - Pulmonary alveolar proteinosis
T2 - An uncommon cause of chronic neonatal respiratory distress
AU - Coleman, M.
AU - Dehner, L. P.
AU - Sibley, R. K.
AU - Burke, B. A.
AU - L'Heureux, P. R.
AU - Thompson, T. R.
PY - 1980
Y1 - 1980
N2 - A full-term newborn infant had the onset of respiratory distress immediately after birth. She required supplemental oxygen from birth, and had pulmonary alveolar proteinosis (PAP) documented by open lung biopsies at 6 and 12 weeks of age. Light and electron microscopy showed dense, PAS-positive granular, homogeneous material within the alveolar spaces, diagnostic of PAP. No Pneumocystis carinii organisms were demonstrated on silver staining, and bacterial and viral cultures were negative. The infant died of progressive respiratory insufficiency at 1 yr of age. Pulmonary alveolar proteinosis should be considered a rare cause of chronic respiratory distress in the newborn infant.
AB - A full-term newborn infant had the onset of respiratory distress immediately after birth. She required supplemental oxygen from birth, and had pulmonary alveolar proteinosis (PAP) documented by open lung biopsies at 6 and 12 weeks of age. Light and electron microscopy showed dense, PAS-positive granular, homogeneous material within the alveolar spaces, diagnostic of PAP. No Pneumocystis carinii organisms were demonstrated on silver staining, and bacterial and viral cultures were negative. The infant died of progressive respiratory insufficiency at 1 yr of age. Pulmonary alveolar proteinosis should be considered a rare cause of chronic respiratory distress in the newborn infant.
UR - http://www.scopus.com/inward/record.url?scp=0018881116&partnerID=8YFLogxK
U2 - 10.1164/arrd.1980.121.3.583
DO - 10.1164/arrd.1980.121.3.583
M3 - Article
C2 - 7416585
AN - SCOPUS:0018881116
SN - 0003-0805
VL - 121
SP - 583
EP - 586
JO - American Review of Respiratory Disease
JF - American Review of Respiratory Disease
IS - 3
ER -