Ptosis as a remote effect of therapeutic botulinum toxin B injection

B. A. Racette; G. Lopate; L. Good; S. Sagitto; J. S. Perlmutter

doi:10.1212/WNL.59.9.1445

Ptosis as a remote effect of therapeutic botulinum toxin B injection

B. A. Racette, G. Lopate, L. Good, S. Sagitto, J. S. Perlmutter

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

The authors report a patient with cervical dystonia, previously treated with botulinum toxin A (BTX-A), who developed bilateral ptosis and difficulty with accommodation only after botulinum toxin B (BTX-B). High-frequency repetitive nerve stimulation of the abductor digiti minimi demonstrated a 34% increment in compound muscle action potential. No increment in 20 people injected with BTX-A and no cases of ptosis in a chart review of 1,606 BTX-A injections for cervical dystonia were found. The authors conclude that systemic spread of BTX-B can cause symptomatic involvement of autonomic neurons.

Original language	English
Pages (from-to)	1445-1447
Number of pages	3
Journal	Neurology
Volume	59
Issue number	9
DOIs	https://doi.org/10.1212/WNL.59.9.1445
State	Published - Nov 12 2002

Access to Document

10.1212/WNL.59.9.1445

Cite this

@article{08b83a42dec64ce7afe311a46eed1247,

title = "Ptosis as a remote effect of therapeutic botulinum toxin B injection",

abstract = "The authors report a patient with cervical dystonia, previously treated with botulinum toxin A (BTX-A), who developed bilateral ptosis and difficulty with accommodation only after botulinum toxin B (BTX-B). High-frequency repetitive nerve stimulation of the abductor digiti minimi demonstrated a 34% increment in compound muscle action potential. No increment in 20 people injected with BTX-A and no cases of ptosis in a chart review of 1,606 BTX-A injections for cervical dystonia were found. The authors conclude that systemic spread of BTX-B can cause symptomatic involvement of autonomic neurons.",

author = "Racette, {B. A.} and G. Lopate and L. Good and S. Sagitto and Perlmutter, {J. S.}",

year = "2002",

month = nov,

day = "12",

doi = "10.1212/WNL.59.9.1445",

language = "English",

volume = "59",

pages = "1445--1447",

journal = "Neurology",

issn = "0028-3878",

number = "9",

}

TY - JOUR

T1 - Ptosis as a remote effect of therapeutic botulinum toxin B injection

AU - Racette, B. A.

AU - Lopate, G.

AU - Good, L.

AU - Sagitto, S.

AU - Perlmutter, J. S.

PY - 2002/11/12

Y1 - 2002/11/12

N2 - The authors report a patient with cervical dystonia, previously treated with botulinum toxin A (BTX-A), who developed bilateral ptosis and difficulty with accommodation only after botulinum toxin B (BTX-B). High-frequency repetitive nerve stimulation of the abductor digiti minimi demonstrated a 34% increment in compound muscle action potential. No increment in 20 people injected with BTX-A and no cases of ptosis in a chart review of 1,606 BTX-A injections for cervical dystonia were found. The authors conclude that systemic spread of BTX-B can cause symptomatic involvement of autonomic neurons.

AB - The authors report a patient with cervical dystonia, previously treated with botulinum toxin A (BTX-A), who developed bilateral ptosis and difficulty with accommodation only after botulinum toxin B (BTX-B). High-frequency repetitive nerve stimulation of the abductor digiti minimi demonstrated a 34% increment in compound muscle action potential. No increment in 20 people injected with BTX-A and no cases of ptosis in a chart review of 1,606 BTX-A injections for cervical dystonia were found. The authors conclude that systemic spread of BTX-B can cause symptomatic involvement of autonomic neurons.

UR - http://www.scopus.com/inward/record.url?scp=0037069307&partnerID=8YFLogxK

U2 - 10.1212/WNL.59.9.1445

DO - 10.1212/WNL.59.9.1445

M3 - Article

C2 - 12427903

AN - SCOPUS:0037069307

SN - 0028-3878

VL - 59

SP - 1445

EP - 1447

JO - Neurology

JF - Neurology

IS - 9

ER -

Ptosis as a remote effect of therapeutic botulinum toxin B injection

Abstract

Access to Document

Other files and links

Fingerprint

Cite this