TY - JOUR
T1 - Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type
AU - Drevets, Wayne C.
AU - Rubin, Eugene H.
N1 - Funding Information:
From tbe Department of Psychiatry and the Alzheimer’s Disease Research Center, Washington University School of Medicine, St, Louis, MO. Supported in part by NIA Grants AGO391 1 and AGO568 1. Address reprint requests to Dr. E.H. Rubin; Department of Psychiatry, Washington University School of Medicine. 4940 Audubon Avenue, St. Louis, MO 63110. Received October 28, 1987; revised February 18, 1988.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Delusions, misidentifications and hallucinations occur frequently throughout the course of senile dementia of the Alzheimer type (SDAT). Rates of psychosis among subjects with moderate to severe SDAT range from 42% to 84% in our study group; at least half of persons with SDAT with no prior psychiatric history will display psychosis at some point during the course of dementia. Furthermore, psychotic symptoms are associated with accelerated cognitive deterioration, but not with increased mortality.
AB - Delusions, misidentifications and hallucinations occur frequently throughout the course of senile dementia of the Alzheimer type (SDAT). Rates of psychosis among subjects with moderate to severe SDAT range from 42% to 84% in our study group; at least half of persons with SDAT with no prior psychiatric history will display psychosis at some point during the course of dementia. Furthermore, psychotic symptoms are associated with accelerated cognitive deterioration, but not with increased mortality.
UR - http://www.scopus.com/inward/record.url?scp=0024578269&partnerID=8YFLogxK
U2 - 10.1016/0006-3223(89)90145-5
DO - 10.1016/0006-3223(89)90145-5
M3 - Article
C2 - 2912509
AN - SCOPUS:0024578269
VL - 25
SP - 39
EP - 48
JO - Biological Psychiatry
JF - Biological Psychiatry
SN - 0006-3223
IS - 1
ER -