Psychiatric Disorder and Quality of Life in Patients Awaiting Lung Transplantation

Priti I. Parekh, James A. Blumenthal, Michael A. Babyak, Kari Merrill, Robert M. Carney, R. Duane Davis, Scott M. Palmer

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Study objective: To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation. Setting: Duke University Medical Center/Lung Transplantation Program. Participants: One hundred patients with end-stage pulmonary disease listed for lung transplantation. Measurements and results: Twenty-five percent (n = 25) of the sample met diagnostic criteria for at least one current mood or anxiety disorder. Controlling for age, gender, ethnicity, percentage of predicted FEV, and lung disease diagnosis, patients with a current psychiatric diagnosis reported poorer general quality of life (p < 0.0001), poorer disease-specific quality of life (p < 0.0001), greater shortness of breath (p = 0.01), more symptoms of psychological distress (p < 0.0001), lower levels of social support (p < 0.0001), and fewer positive health habits (p < 0.04) than their counterparts without a psychiatric diagnosis. Conclusions: Psychiatric comorbidity affects a significant portion of patients awaiting lung transplantation and is associated with decreased health-related quality of life.

Original languageEnglish
Pages (from-to)1682-1688
Number of pages7
Issue number5
StatePublished - Nov 2003


  • Anxiety
  • Depression
  • Lung transplantation
  • Psychiatric disorder
  • Quality of life


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