Proton NMR imaging of cerebral blood flow using H217O

  • K. K. Kwong
  • , A. L. Hopkins
  • , J. W. Belliveau
  • , D. A. Chesler
  • , L. M. Porkka
  • , R. C. McKinstry
  • , D. A. Finelli
  • , G. J. Hunter
  • , J. B. Moore
  • , R. G. Barr
  • , B. R. Rosen

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H217O using rapid, single‐shot proton NMR imaging. H217O acts as a freely diffusible contrast agent for proton imaging via its scalar‐coupled term, enhancing T2 relaxation. Measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO2 between 23 and 81 Torr. © 1991 Academic Press, Inc.

Original languageEnglish
Pages (from-to)154-158
Number of pages5
JournalMagnetic resonance in medicine
Volume22
Issue number1
DOIs
StatePublished - Nov 1991

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