Proton NMR imaging of cerebral blood flow using H217O

K. K. Kwong, A. L. Hopkins, J. W. Belliveau, D. A. Chesler, L. M. Porkka, R. C. McKinstry, D. A. Finelli, G. J. Hunter, J. B. Moore, R. G. Barr, B. R. Rosen

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Abstract

Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H217O using rapid, single‐shot proton NMR imaging. H217O acts as a freely diffusible contrast agent for proton imaging via its scalar‐coupled term, enhancing T2 relaxation. Measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO2 between 23 and 81 Torr. © 1991 Academic Press, Inc.

Original languageEnglish
Pages (from-to)154-158
Number of pages5
JournalMagnetic resonance in medicine
Volume22
Issue number1
DOIs
StatePublished - Nov 1991
Externally publishedYes

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    Kwong, K. K., Hopkins, A. L., Belliveau, J. W., Chesler, D. A., Porkka, L. M., McKinstry, R. C., Finelli, D. A., Hunter, G. J., Moore, J. B., Barr, R. G., & Rosen, B. R. (1991). Proton NMR imaging of cerebral blood flow using H217O. Magnetic resonance in medicine, 22(1), 154-158. https://doi.org/10.1002/mrm.1910220116