Protecting P-type plasma membrane H+-ATPases from ROS

Sarah C. Stainbrook, Joseph M. Jez

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


P-type ATPase are ubiquitous transport proteins across all kingdoms of life. These proteins share a common mechanism involving phosphorylation of an invariant aspartate to facilitate movement of substrates from protons to phospholipids across cellular membranes. In this issue of the Biochemical Journal, Welle et al. identify a conserved cysteine near the functionally critical aspartate of P-type plasma membrane H+-ATPases that protects the protein from reactive oxygen species.

Original languageEnglish
Pages (from-to)1511-1513
Number of pages3
JournalBiochemical Journal
Issue number8
StatePublished - Apr 2021


Dive into the research topics of 'Protecting P-type plasma membrane H+-ATPases from ROS'. Together they form a unique fingerprint.

Cite this