Prosurvival and antiapoptotic effects of PGE₂ in radiation injury are mediated by EP₂ receptor in intestine

Keyphrases

• Adult Mice 16%
• Anti-apoptosis 100%
• Apoptosis 16%
• Apoptotic Cells 33%
• Biological Activity 16%
• Crypt 100%
• Crypt Survival 16%
• EP Receptors 16%
• EP2 Receptor 100%
• Epithelial Cell Apoptosis 33%
• G Protein-coupled Receptor 16%
• Gastrointestinal 16%
• Intestinal Crypt Stem Cell 16%
• Intestinal Epithelial Cells 16%
• Intestinal Stem Cells 16%
• Intestine 100%
• Irradiation 16%
• Ligand Binding 16%
• Littermate 33%
• Null Mice 16%
• Plasma Membrane 16%
• Pro-survival 100%
• Prostaglandin E2 100%
• Radiation Damage 100%
• Radiation-induced Apoptosis 16%
• Receptor Expression 16%
• Signal Transduction Pathway 16%
• Stem Cell Survival 33%
• Wild Mice 16%

Biochemistry, Genetics and Molecular Biology

• Biological Activity 25%
• Cell Membrane 25%
• Cell Survival 50%
• EP1 Receptor 25%
• G Protein Coupled Receptor 25%
• Grand Unified Theory 25%
• Knockout Mouse 25%
• Ligand Binding 25%
• Messenger RNA 25%
• Programmed Cell Death 100%
• Signal Transduction 25%
• Stem Cell 50%
• Wild Type 50%
• Wild Type Mouse 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Antiapoptotic 100%
• Biological Activity 20%
• G Protein Coupled Receptor 20%
• Knockout Mouse 20%
• Messenger RNA 20%
• Radiation Injury 100%
• Receptor 100%
• Wild Type Mouse 20%