Prostate Cancer With Peritoneal Carcinomatosis: A Robotic-assisted Radical Prostatectomy-based Case Series

Steven B. Goldenthal, Melissa A. Reimers, Udit Singhal, Mark Farha, Rohit Mehra, Morand Piert, Jeffrey J. Tosoian, Parth K. Modi, Nicole Curci, James Peabody, Eduardo Kleer, David C. Smith, Todd M. Morgan

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To aid in the diagnosis and treatment of patients with metastatic tumor seeding, an exceedingly rare phenomenon following minimally invasive urological surgery, additional case reports are needed. Materials and Methods: We report our experience with patients determined to have peritoneal carcinomatosis following robotic-assisted radical prostatectomy (RARP) and provide a descriptive summary of these unique cases. Results: Five cases of peritoneal carcinomatosis were identified, all of which occurred relatively late—between 8 and 13 years—following RARP. Four of the 5 cases had T3 disease at the time of prostatectomy. 68Ga-PSMA PET identified peritoneal carcinomatosis in 3 of 5 cases. Conclusion: Certain clinical factors, such as advanced pathologic stage at the time of prostatectomy, may predict risk for carcinomatosis following RARP. Additionally, next-generation imaging modalities, such as PSMA PET, may aid in identifying these metastases and are likely to identify increasing numbers of these patients as next-generation imaging becomes more widely available. Continued documentation and classification of this atypical presentation are needed to improve our understanding and management of this phenomenon.

Original languageEnglish
JournalUrology
DOIs
StateAccepted/In press - 2022

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