TY - JOUR
T1 - Prospective Study of Relative Weight, Height, and Risk of Breast Cancer
AU - London, Stephanie J.
AU - Colditz, Graham A.
AU - Stampfer, Meir J.
AU - Willett, Walter C.
AU - Rosner, Bernard
AU - Speizer, Frank E.
PY - 1989/11/24
Y1 - 1989/11/24
N2 - We examined relative weight and height in relation to subsequent breast cancer risk among 115 534 women 30 to 55 years of age and free from cancer in 1976. By 1984, six hundred fifty-eight premenopausal and 420 postmenopausal breast cancers were documented during 734 716 person-years. Among premenopausal women, risk of breast cancer decreased significantly with increasing relative weight (relative risk for the highest category was 0.6). A similar inverse association was seen for recalled relative weight at 18 years of age. Postmenopausal breast cancer was not associated with relative weight, either recent or at age 18. Height was not associated with breast cancer risk among premenopausal women and only weakly related among postmenopausal women. These data suggest that obesity among premenopausal and early postmenopausal women does not increase breast cancer risk substantially.
AB - We examined relative weight and height in relation to subsequent breast cancer risk among 115 534 women 30 to 55 years of age and free from cancer in 1976. By 1984, six hundred fifty-eight premenopausal and 420 postmenopausal breast cancers were documented during 734 716 person-years. Among premenopausal women, risk of breast cancer decreased significantly with increasing relative weight (relative risk for the highest category was 0.6). A similar inverse association was seen for recalled relative weight at 18 years of age. Postmenopausal breast cancer was not associated with relative weight, either recent or at age 18. Height was not associated with breast cancer risk among premenopausal women and only weakly related among postmenopausal women. These data suggest that obesity among premenopausal and early postmenopausal women does not increase breast cancer risk substantially.
UR - http://www.scopus.com/inward/record.url?scp=0024306997&partnerID=8YFLogxK
U2 - 10.1001/jama.1989.03430200097033
DO - 10.1001/jama.1989.03430200097033
M3 - Article
C2 - 2810620
AN - SCOPUS:0024306997
SN - 0098-7484
VL - 262
SP - 2853
EP - 2858
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 20
ER -