Propofol use in pediatric patients with food allergy and eosinophilic esophagitis

Pooja Mehta, Shikha S. Sundaram, Glenn T. Furuta, Zhaoxing Pan, Dan Atkins, Scott Markowitz

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Propofol is a safe, well-tolerated anesthetic that is labeled as contraindicated in patients with egg or soy allergy. This contraindication has become increasingly problematic given the rising incidence of food allergy and eosinophilic esophagitis (EoE). To address this issue, we studied practice patterns of propofol use for esophagogastroduodenoscopies in children with EoE and food allergies at our institution. A retrospective observational study of 1365 esophagogastroduodenoscopies from January 2013 to June 2014 was performed. Data were analyzed using Student t tests, chi square tests, Fisher exact tests, and multivariable logistic regression. We found that propofol was used significantly less in patients with egg or soy allergy, and in patients with EoE, even after adjusting for the presence of food allergy. There was no difference in complication rates relative to propofol use. Propofol was used safely in pediatric patients with EoE and food allergy in this limited single-center review.

Original languageEnglish
Pages (from-to)546-549
Number of pages4
JournalJournal of pediatric gastroenterology and nutrition
Volume64
Issue number4
DOIs
StatePublished - Apr 1 2017

Keywords

  • anesthesia
  • egg allergy
  • soy allergy

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