Propofol infusion platforms

Preet Mohinder Singh, Basavana G. Goudra

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Propofol is the most popular drug used for sedation assisted procedures. Many drug delivery systems taking advantage of propofol pharmacokinetics are available in the market. Target controlled infusion systems have strong evidence in support of their use in the operating room. TCIs help to maintain a constant sedation level via computer generated propofol dosing regimens. Many new studies have shown that propofol based TCI guided sedation has the potential to alter patient outcomes, decrease sedation provider's workload and allow rapid patient turnovers in a busy sedation suite. Going one step further, new personalized sedation concept has emerged. Sedasys is a recently approved semi-automatic propofol based sedation delivery system. Sedasys can be used for mild to moderate sedation in adults undergoing gastroenterological endoscopic procedures. It uses a computer based dosing protocol based upon patient's demographic parameters. Sedasys continuously monitors the sedation depth using patient's responsiveness to automated verbal stimulus and can lower the propofol doses if needed.

Original languageEnglish
Title of host publicationOut of Operating Room Anesthesia
Subtitle of host publicationA Comprehensive Review
PublisherSpringer International Publishing
Number of pages9
ISBN (Electronic)9783319391502
ISBN (Print)9783319391489
StatePublished - Sep 29 2016


  • Propofol delivery systems
  • Sedasys
  • Target controlled infusions


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