Proneurotrophin-3 is a neuronal apoptotic ligand: Evidence for retrograde-directed cell killing

Keyphrases

• Cell Killing 100%
• Proneurotrophins 100%
• Sympathetic Neurons 75%
• Neurotrophin-3 (NT-3) 50%
• Neurotrophins 50%
• Neuron Death 50%
• Apoptosis 25%
• Recombinant 25%
• Axon 25%
• Kinase Activation 25%
• Dysregulation 25%
• Nervous System 25%
• High Affinity 25%
• Cerebellar Granule Neurons 25%
• HEK293 Cells 25%
• Bona Fide 25%
• Pharmacological Inhibitors 25%
• Neural Tissue 25%
• C-Jun N-terminal Kinase 25%
• Survival Signaling 25%
• Neuronal Survival 25%
• Retrograde Transport 25%
• Transport Mechanism 25%
• Distal Axons 25%
• Trophic Factors 25%
• Non-neural 25%
• Membrane Depolarization 25%
• Culture System 25%
• Neuronal Cell Bodies 25%
• Furin 25%
• P75 Neurotrophin Receptor (p75NTR) 25%
• Nuclear Fragmentation 25%
• Peripheral Innervation 25%
• Neural Population 25%
• Compartmentalized Culture 25%
• Proteinase Activity 25%
• Sortilin 25%
• Localized Action 25%

Biochemistry, Genetics and Molecular Biology

• Axon 100%
• Precursor 100%
• Neurotrophin 100%
• Cell Killing 100%
• Neurotrophin-3 100%
• Secretion (Process) 50%
• Kinase 50%
• Phosphotransferase 50%
• N-Terminus 50%
• Innervation 50%
• Membrane Depolarization 50%
• Furin 50%
• Protease 50%
• Programmed Cell Death 50%

Neuroscience

• Neurotrophin-3 100%
• Neurotrophin 100%
• Cell Killing 100%
• Axon 100%
• Innervation 50%
• Kinase 50%
• Nerve Tissue 50%
• Nervous System 50%
• Amino Terminal Sequence 50%
• Proteinase 50%
• Membrane Depolarization 50%
• Furin 50%
• Programmed Cell Death 50%