Promotion of reprogramming to ground state pluripotency by signal inhibition

Keyphrases

• Signal Inhibition 100%
• Ground State Pluripotency 100%
• Neural Stem Cells 100%
• Leukemia Inhibitory Factor 100%
• Octamer-binding Transcription Factor 4 (OCT4) 100%
• Epigenetics 66%
• Nanog 66%
• Induced Pluripotent Stem Cells (iPSCs) 66%
• Chimera 66%
• Somatic Cells 66%
• X Chromosome 66%
• Germ Cells 33%
• Transgene Integration 33%
• Stable Expression 33%
• KLF4 33%
• Pluripotent Cells 33%
• High Efficiency 33%
• Sex-determining Region Y-box 2 (SOX2) 33%
• Defined Conditions 33%
• Mitogen-activated Protein Kinase 33%
• Molecular Dissection 33%
• Pluripotent Stem Cells 33%
• Glycogen Synthase Kinase 3 (GSK3) 33%
• State Influence 33%
• C-Myc 33%
• Stem Cell Reprogramming 33%
• Deprogramming 33%
• Rare Cells 33%
• Multiple Transgenes 33%
• Pluripotency 33%
• Cell State 33%
• Transgene Silencing 33%
• Brain-inspired 33%
• Factor Condition 33%
• Reprogramming Factors 33%
• Tissue Stem Cells 33%
• Dual Inhibition 33%
• Chimaerism 33%
• Self-renewal 33%
• Genetic Manipulation 33%

Biochemistry, Genetics and Molecular Biology

• Reprogramming 100%
• Stem Cell 100%
• Transgene 60%
• Leukemia Inhibitory Factor 60%
• X Chromosome 40%
• Somatic Cell 40%
• Nanog 40%
• Epigenetics 40%
• Induced Pluripotent Stem Cell 40%
• Germline 20%
• Germ Cell 20%
• Mitogen-Activated Protein Kinase 20%
• Upregulation 20%
• Cytokine 20%
• Stable Expression 20%
• Glycogen Synthase Kinase 3 20%
• Nuclear Reprogramming 20%
• Genetic Manipulation 20%
• Oncogene C Myc 20%
• Chimera 20%